SenTraGor™ is an innovative reagent for the detection of senescence. Senescent cells play a potent role in normal development, tissue homeostasis, aging and a wide spectrum of age related disorders. Up to now, a major problem in the field of senescence was the absence of a reliable marker to specifically detect these cells, especially in situ. SenTraGor™ is a biotinylated Sudan Black B based chemical reagent that was designed to overcome this constraint.
SenTraGor™ staining allows the detection of senescence in any biological material. Direct visualization of senescent cells can be achieved in all archival tissue specimens (formalin-fixed paraffin-embedded) and cells from biopsies or cell cultures.
SenTraGor™ reagent can be used in different applications. You can read, view pictures and download the detailed step by step protocols for Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry Analysis (FACS), as well as double stainings.
Publications featuring SenTraGor™ reagent's use in different biological materials